The STI API Prevention Database is a curated, centralized resource designed to support researchers focused on the prevention of sexually transmitted infections (STIs), including human immunodeficiency virus (HIV) and multipurpose prevention technologies (MPTs). It provides essential information on compounds and active pharmaceutical ingredients (APIs) with known or potential STI prevention applications. By identifying and cataloging promising pharmaceutical candidates, the database empowers STI prevention researchers to advance science and accelerate innovation. It also serves as a valuable tool for MPT developers, promoting cross-disciplinary collaboration and information sharing between the traditionally siloed fields of contraception and anti-infective research to drive product development forward.
This database provides detailed information on each candidate and allows users to filter results using drop-down menus.
| CAS Number | Compound Name | Research & Development Stage | Regulatory Status | Drug Class | Spectrum of Activity | Route of Administration | Drug Delivery System | Funding Source | Product Details |
|---|---|---|---|---|---|---|---|---|---|
| Other | Test compound | Preclinical Development | Yes | Test Drug | Herpes simplex virus (HSV) 1, Bacterial vaginosis (BV) | Systemic, Other | Film, Microarray Patch | Other | |
| 73384-59-5 | Doxycycline | Clinical Development: Phase 2 | Yes | Antiviral, Antifungal | Human papillomavirus (HPV), Bacterial vaginosis (BV) | Systemic, Vaginal | Fast Dissolving Insert, Intravaginal Ring | CDC, NIH |
Know of an MPT product not included in this database or have updated information for listed products? Let us know here!